Reversal of Occlusal Caries with Ozone after Six Months
By G Megighian and
Private practice, Verona, Italy
use of ozone using HealOzone technology allows the treatment
of a vast range of dental caries at a very early stage
and to induce lesion remineralisation from saliva. Such
methodology has the potential to be the alternative to
the conventional drilling and filling of dental caries.
Objectives: The aim of this randomised,
double blind clinical trial was to longitudinally monitor
pit and fissure carious lesions (PFCLs) using light-induced
fluorescence readings using a clinical classification of PFCLs
as well as the DIAGNOdent (KaVo Germany), and to quantify
the effects of Ozone application on these readings after six
Methods: A total of 300 PFCLs were entered
in 80 patients. After cleaning each lesion using air abrasion
with 27.5 micron particles, a clinical severity index and
DIAGNOdent (KaVo, Germany) standard scale readings were recorded.
220 lesions were treated at baseline with Ozone (using the
HealOzone unit from CurOzone USA and KaVo Germany) for 20,
30 or 40 seconds according to their clinical severity, after
one other lesion (receiving no Ozone) was randomised as control
in each Patient. The clinical severity indices and DIAGNOdent
readings were repeated after six months to evaluate changes
on both the test and control lesions.
Results: Ozone treated lesions clinically
reversed (P<0.05) whilst control lesions did not change.
A significant overall reduction of DIAGNOdent readings was
associated with Ozone treatment after six months. The percentage
of teeth which clinically reversed and produced this reduction
was 85% (p<0.05). In contrast, the control lesions showed
increased Diagnodent readings (P<0.05).
Conclusion: The results demonstrate the effectiveness
of Ozone to clinically reverse occlusal pit and fissure caries
lesions and to also reduce their Diagnodent readings after
Keywords: Cariology, Diagnosis, Clinical
trials, Human, Quality of life
Giovanni Megighian, BDS, Private practice,Verona, Italy
L Bertolini, BDS, Private practice,Verona, Italy