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Research

Ozone management of occlusal pit and fissure caries (PFC): 12-month review
by L Abu-Naba'a, H AL Shorman and E Lynch
Oral Health Research Centre, School of Dentistry, Queen's University Belfast, NI
Ozone is investigated as a pharmaceutical treatment for primary occlusal pit and fissure caries (PFC) in a longitudinal controlled clinical trial.

Aim
To monitor lesions' remineralisation, arrest or progression as with/without ozone treatment and assess fissure sealant retention over treated lesions.

Methods
Permanent teeth with non-cavitated PFC in 89 patients were enrolled. Teeth were cleaned using air-abrasive system (Prophyflex 2®, KaVo, Germany), then the following were recorded: clinical severity (Ekstrand KR et al, Caries Res. 1998;32:247-54.), DIAGNOdent® (KaVo, Germany) and ECM IV (LODE BV, Netherlands) standard scale readings. After randomisation, 195 lesions were treated with Ozone for 10 seconds (HealOzone unit, CurOzone USA) and the other half were reserved as controls. 66 of the treatment group and 66 in the control group further received a fissure sealant (Guardian®, Kerr). For the unsealed teeth, the procedure was repeated at 1, 3, 6, 9 and 12 months (m) while those sealed only had their sealants checked by Modified USPHS criteria for sealant quality. The changes in readings were tested from baseline by t-test of (loge recall value/base value), and paired t-test between various groups and 2-way analysis for block and treatment effects. The effect of co-variables was tested.

Results
No adverse effect was recorded. Mean change in ECM was 0.337 and -0.065 for the treatment and control groups respectively. Difference between groups was better in treatment group from the first month recall (p<0.05) with the highest change in the 3m recall. Change in the clinical severity and DIAGNOdent scores stabilised in the treatment group from the 3 and 6m recalls respectively. At all recalls these scores were higher for the control group than the treatment group (p=0.081). None of the co-variables tested had any effect on the results. No significant difference was found in the short and long term retention of sealants in both sealant groups.

Conclusion
Ozone treatment significantly remineralised lesions regardless to tooth or lesion location or type, while lesions in the control group suffered from deterioration in their mineral content. With no significant loss of Fissure sealant retention, sealing after ozone treatment can best be after 3 months of treatment.

KaVo Press Release

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