effective, low-cost treatments for many diseases, including
HIV and cancer
a time when orthodox medical research, especially into
cancer treatments, seems intent on exploring drugs and
techniques whose usually expensive, benefits are offset
by equally damaging side-effects, it is strange that applications
that have been used very successfully by many doctors
in certain countries to treat a vast array of degenerative
illness, including cancer, heart disease and HIV/AIDS,
are virtually ignored, particularly when existing studies
indicate their considerable potential both to save life
and huge sums of money for a country's health service.
Oxygen is so obviously vital to life that the role of chronic,
sub-clinical deprivation may easily be overlooked in its profound
contribution to the development of so much disease. But as
long ago as 1931 the German doctor and scientist Otto Warburg
won a Nobel Prize for his work on the fundamental importance
of oxygen-transfer in cell respiration; in 1944 he won a second
for his discovery of the hydrogen-transferring enzyme.
In his 1966 book, The Prime Cause and Prevention of Cancer
(Wurzburg: K Tritsch), Warburg, a director of The Max Planck
Institute for Cell Physiology, stated:
'Cancer, above all other diseases, has countless secondary
causes, but there is only one prime cause
of the normal oxygen respiration of body cells by an anaerobic
[oxygen lacking] cell respiration.'
What he showed was that the growth of cancer cells is initiated
by a relative lack of oxygen at the cellular level. When cells
cannot get sufficient oxygen they start to feed off themselves
in a sugar fermentation process that gets progressively disruptive,
leading to a toxic environment in which cancer and other illnesses,
triggered by viruses and parasites, can thrive. Cancer cells
cannot easily exist in a high oxygen environment.
Bacteria and parasites in the gut divide into two main types:
the beneficial, such as Lactobacillus and Acidophillus, which
are mainly aerobic, and the harmful, such as E coli, Staphylococcus
and Helicobacter pylori, which are anaerobic. Thus, with sufficient
oxygenation, the beneficial 'bugs' thrive, while the harmful
are keep under control. But if oxygen saturation falls below
a critical level - around 60% - the reverse process begins
to occur which, chronically, enables a host of diseases to
To combat such disease and restore adequate oxygenation, thus
ensuring proper oxidation, bio-oxidative therapies, in the
form of ozone and hydrogen peroxide (and, to a lesser extent,
hyperbaric oxygen), have been used for over 100 years. First
appearing in mainstream medical journals in 1920, they were
increasingly used by European practitioners, but in the US
were suppressed and doctors persecuted at the hands of the
FDA. Only now are they starting to attract mainstream interest,
due in part to the spectre of antibiotic resistance, with
some 50-100 references appearing in world medical journals
In Nature ozone occurs in the atmosphere and is formed when
ultraviolet radiation forces oxygen to recombine temporarily
in groups of three atoms, as an energised form of oxygen (O3),
which quickly reacts with other substances. It is also produced
during an electrical storm and the characteristic smell afterwards
is due to the small amount of ozone in the air.
It is produced commercially in ozone generators, which use
an electrical charge through a condenser, and has been used
to purify water since 1860 when the first treatment plant
was built in Monaco. In 1901 Werner von Siemens (founder of
the drug company) treated water with it for the first time
in Germany. Today over 3,000 cities use ozone to treat their
In September 1896, the electrical genius Nikola Tesla patented
his first ozone generator and in 1900 he formed the Tesla
Ozone Co. Tesla sold ozone machines and ozonated olive oil
to doctors for medical use.Ozone is also used by the bottling,
pharmaceutical and food industries as a disinfectant as well
as to clean up polluted lakes or rivers, which it does far
more effectively than chlorine without killing animal life
or leaving harmful chemical residues. Ozone is also an effective
air cleaner and remover of noxious odours.
During World War 1 the Germans used ozone to treat wounds
and infections. In the 1930s German scientists and doctors
carried out considerable research into its effects, using
it to successfully treat Crohn's disease, ulcerative colitis,
inflammatory bowel disease and chronic bacterial diarrhea.
A German dentist, Dr EA Fisch, first used ozonated water as
a disinfectant; one of his patients, surgeon Dr Erwin Payr,
in 1945 pioneered the method of injecting ozone intravenously
to treat circulatory problems.
Another German pioneer, physicist Joaquim Hansler developed
the first medical ozone generator that could make accurate
doses of oxygen and ozone, and the company he founded is now
the largest manufacturer of medical ozone generators in the
world. The lead by German doctors in this field led to Dr
W Zable in the late 1950's becoming the first to treat cancer
with ozone, while Dr Horst Kief, near Frankfurt, is believed
to have been the first doctor to use it to treat HIV.
Today, an estimated 9,000 licensed health practitioners in
Germany use ozone, compared to a handful in the UK. Another
8,000 practitioners across Europe are using it. It is generally
given by rectal insufflation, injection, autohemotherapy (in
which blood is extracted, treated and then returned to the
body), by steam cabinet, body bag and, under special conditions,
It is estimated that over 10 million ozone treatments have
been given to over 1 million patients in Germany alone over
the last 40 years. Despite this extraordinary record the American
FDA continues to obstruct human trials there and actively
prosecutes US doctors for using ozone.
Created in the atmosphere when ultraviolet light strikes oxygen
in the presence of moisture, hydrogen peroxide is a clear,
colourless liquid that mixes easily with water. Composed of
two atoms of oxygen and two of hydrogen (H2O2), hydrogen peroxide
is involved in all of the essential processes of life and
must be present for the immune system to function properly.
The latter's first line of defence against viruses, bacteria,
parasites and yeast is hydrogen peroxide produced by granulocytes,
white blood cells that fight infection. Hydrogen peroxide
is also necessary both to help metabolise carbohydrates, proteins,
fats, vitamins and minerals, and as a hormone regulator in
the production of oestrogen, progesterone and thyroxin. It
also assists in regulating blood sugar and energy production
For a long time hydrogen peroxide has been used medically
as an antiseptic, disinfectant, and oxidiser. One of its special
qualities is its ready ability to decompose into water and
oxygen. It is also used commercially for bleaching, pollution
control and in agriculture.
It has been found in many of the world's healing springs,
including Lourdes in France, and, most recently, it has treated
a wide variety of diseases, with few side effects.
It is usually administered orally, intravenously or by injection
into joints and soft tissue trigger points, as 30 percent
reagent-grade or 35 percent food-grade hydrogen peroxide.
This therapy uses 100% pure oxygen administered at two to
three times normal atmospheric pressure in a special chamber.
By dissolving oxygen in the blood plasma this results in delivering
increased oxygen directly to tissues. It is best known for
its use in treating carbon monoxide poisoning, gas gangrene
and decompression in divers, known as the 'bends'.
However, hyperbaric oxygen (HBO) therapy is now increasingly
being used as an adjunct to standard medical care because
it not only reduces swelling or oedema but also produces antioxidant
effects and stimulates new blood vessel formation where blood
supply is limited. It is now used to treat anaerobic infections,
chronic bone infections, difficult wounds, crush and soft
tissue injuries, burns, skin grafts and radiation injuries.
It is also useful in treating diabetes, vascular disease,
cancer patients undergoing irradiation, and those recovering
from cosmetic, plastic and laser surgery. Research is looking
at its use for strokes, HIV-linked disorders and chronic fatigue
syndrome. MS patients use it at over 50 centres around the
UK. It is treating sports injuries and some believe that it
enhances athletic performance.
The main research carried out into bio-oxidative therapies
has taken place in Germany, Russia and Cuba, where governments
and universities cooperate and support such studies. To a
far lesser extent research is also taking place in Italy,
France, Mexico, Canada and the USA. Hardly any is happening
in the UK.
In Russia ozone therapy has been approved by the Ministry
of Public Health and is fast becoming part of mainstream medicine.
Institutions such as the Central Scientific Laboratory at
the Medical Institute Nizhni Novgorod (Gorky) and the Central
Scientific Research Institute of Dermatology and Venerology
in Moscow are involved in both research and training of physicians.
Cuba's greatest success since its 1959 revolution - and one
of its main aims - has been to provide a first-class, free
health service for its 11 million people. Despite the crippling
US economic blockade, it has carried out medical ozone research
since 1985 under the auspices of the Department of Ozone,
which works with doctors across the country as part of the
National Program for Ozone Therapy. In 1994 the Department,
with its 60 staff, was relocated at the new Centre for Ozone
Therapy in Havana, which hosted the 2nd International Symposium
on Ozone Applications in 1997. Since 1985 over 20,000 Cubans
have been treated with ozone and many foreigners travel the
country for just this treatment.
Russia and Cuba's eminence in research is due to factors including
both having a history of socialised medicine, limited access
to western drugs, and the very low cost and lack of patentability
- and thus little profit - of producing ozone. In the US the
FDA has been accused by leading campaigner for oxygen therapies
Ed McCabe (author of Oxygen Therapies, Energy Publications,
New York, 1988: available in the UK from Resonance, 01803
840008) of protecting the interests of the drug companies
against the obvious threat posed by ozone by harassing doctors
using it and preventing human trials, although increasing
research evidence is forcing a change in this attitude.
In 1994 the International Oxidative Medicine Association was
founded by Dr Charles Farr in Oklahoma City. Dr Farr, who
sadly died recently, was one of America's leading practitioners
of oxidative medicine and, with over 35 medical publications
to his credit (including The Therapeutic Use of Intravenous
Hydrogen Peroxide, monograph, Oklahoma City, 1987), was nominated
for a Nobel Prize in 1993 for his work.
Other associations include the International Association for
Oxygen Therapies, based in Priest River, Idaho, and the European-based
Medical Society for Ozone, which has branches in Germany,
Austria, Italy and Switzerland.
As double Nobel Prize-winner Dr Otto Warburg showed, cancer
cells cannot exist in a high oxygen environment. In 1974 Dr
Joaquim Varro reported that such cells were inhibited by peroxide
(Erfahrungsheilkunde 23;178-81). This was only confirmed in
an English publication in 1980 when Dr Frederick Sweet and
colleagues reported laboratory evidence that proved that ozone
selectively inhibits the growth of cancer cells (Science,
August 22, 1980; 209:931-2).
In the States early cancer research in the '60s at Baylor
University in Dallas, Texas, by Dr JW Finney and his associates
had shown the value of hydrogen peroxide as an adjunct in
treating cancer by making cancer cells more sensitive to irradiation
(Southern Med J, March 1962). A further study endorsed the
value of H2O2 in shrinking the size of tumours (BL Aronoff
et al. Cancer 1965;18:1250).
A subsequent Japanese study of 15 patients confirmed that
H2O2 enhanced the effect of an anti-cancer agent (H Sasaki
et al. Yonago Acta Medica 1967;11(3):149), while American
researchers in New York reported in 1981: 'Hydrogen peroxide
contributes to the lysis of tumor cells by macrophages and
granulocytes in vitro.' (CF Nathan et al. J Exp Med 1981;154:1548).
More recently, investigating effects on Hodgkin's disease,
researchers at the University of California observed that
'peroxidase in Hodgkin's disease sensitizes the tumor cells
to killing by low levels of hydrogen peroxide.' (MK Samoszuk
et al. Cancer 1989;63:2114).
One of the first reports of successful cancer treatment with
ozone using actual patients was reported, as mentioned above,
by the German Dr Joachim Varro at the Sixth World Ozone Conference
in 1983 and published in Medical Applications of Ozone (Ed.
Julius LaRaus, Norwalk, Conn. pp 94-5). Dr Varro reported
that patients experienced increased appetite, greater strength,
higher rates of physical activity and reduction in pain. He
stated that patients were 'free of metastases and tumour relapses
for remarkably long periods of time; survival time could be
prolonged, far exceeding the usual dubious prognoses, even
in cases of inoperability, radiation resistance, or chemotherapy
non-tolerance, and with improved quality of life. Most patients
who had undergone the combination therapy shortly after surgery
and radiation could return full time to their occupations.'
To explore the suspicion that anti-cancer effects of ozone
are due in part to its ability to induce release of tumour
necrosis factor (TNF), Italian researchers at the University
of Siena measured ozonated blood and observed that most TNF
was released immediately after ozonation took place. (L Paulesu
et al. Lymphokine and Cytokine Res. 1991;10(5):409-12).
At the Hospital Santa Monica in Mexico, founder Dr Kurt Donsbach
uses intravenous H2O2 extensively to treat cancer patients,
and has treated thousands, many of whom make a complete recovery.
In his highly recommended book Oxygen Healing Therapies (Healing
Arts Press, Rochester, Vermont, 1998), author Nathaniel Altman
visited the hospital and asked Dr Donsbach about survival
'Approximately 70 percent of our patients are alive three
years after their first visit
Some are cured, some are
in remission and some are slowly dying. However, very few
of these patients had more than months to live according to
their doctors when they arrived. But what kind of statistics
are these? We see a significant percentage of out patients
become totally and completely cured as documented by medical
diagnostic standards.' (p. 86)
A similar view was given when Altman visited Dr Horst Kief's
clinic in Germany in 1993. The reported long-term remission
rate for cancer patients was given as 60 percent, with another
20 percent experiencing improvement. (ibid, p. 87)
In their book The Use of Ozone in Medicine (Haug Publishers,
Heidelberg, 1987; updated 1994), Drs Siegfried Rilling and
Renate Viebahn state that doctors have used ozone therapy
in angiology, dermatology, gastroenterology, gerontology,
intensive care, gynaecology, neurology, odontology, oncology,
orthopaedics, proctology, radiology, rheumatology, surgery
Wide range of other major uses
Research, especially in Cuba, has covered many areas. Ozone
therapy is now routine in Cuban hospitals for those suffering
from angina and heart attacks. A recent study at their Ozone
Research Center on 22 heart attack patients found that therapy
significantly decreased plasma total cholesterol and low-density
lipoprotein, 'provoking the activation of antioxidant protection
systems' (F Hernandez et al. Free Rad Biol & Med 1995:115-9).
Another Cuban study of ischemic cerebrovascular disease in
120 elderly patients produced impressive results. The mental
and physical condition of all patients improved significantly.
Post-therapy tests showed that the subject's ability to participate
in daily life situations improved in 80 to 95 percent of subjects
in the three groupings (E Devesa at al. in Ozone in Medicine:
Proc 11th Ozone World Congress, Stamford, Conn. Int Ozone
Assoc, 1993: M-4-10-18).
Cuban scientists have also pioneered ozone therapy to treat
eye diseases including glaucoma, corneal ulcers, atrophy of
the optic nerve and diabetic retinopathy. They have had particular
success in treating retinitis pigmentosa; in one study 89
percent of the 175 patients studied showed marked improvement
that persisted for 2 years after treatment, while a 10-year
study of 20 patients found that the best results were achieved
when treatment was repeated twice a year, showing improvements
of 70 percent in visual field and 42 percent in visual acuity
(M Copello et al. in Abstrs.: 2nd Int. Symposium on Ozone
Applications, Havana: Ozone Research Center, 1997:36).
At the same symposium Cuban doctors reported their success
with 80 patients suffering from hepatitis A, B and C. Those
receiving ozone were diagnosed as cured after 3 weeks; the
control group took 6 months (Y Betancourt et al. ibid. pp
Skin diseases have also been successfully treated by Cuban
doctors. In a study of herpes zoster (shingles), treated with
ozonated sunflower oil and intramuscular injections for 15
days, all 15 patients showed marked improvement after only
three applications and were judged symptom-free by the end
of treatment , with no relapse after one year's follow-up
(J Delgado, Revista CENIC Ciencias Biologicas 1993;20:160-2).
Similar results have been obtained by Dr Heinz Conrad in Brazil
(Proc: Ozone in Medicine, 12th World Congress of the Int Ozone
Assoc., Zurich, Int Ozone Assoc., 1995:189).
Other research has reported success in treating arthritis,
asthma, dementia, diabetes, flu, giardiasis, Lyme disease,
osteoporosis, sickle cell anaemia, TB and wounds.
In a very recent review article, with 101 references, Professor
V Bocci at the University of Siena presents the case for re-admitting
ozone therapy to the medical mainstream from which it was
excluded by the growing domination of drug therapy many years
ago (Br J Biomed Sci. 1999;56:270-9).
Clearly, British oncologists and other specialists have much
to learn about oxidative therapies that would greatly help
their patients - with virtually no side-effects - and potentially
save the NHS a fortune in ongoing unnecessary drug usage.
Where to get treatment in the UK
Aside from hyperbaric oxygen therapy, there is only a handful
of doctors offering treatment with ozone or hydrogen peroxide
in the UK. One is Dr Patrick Kingsley, based in Osgathorpe,
Leicestershire, who has used H2O2 for three years, chiefly
for cancer, ME, MS and candida. A member of the International
Oxidative Medicine Association, he visits the States regularly,
attending conferences and keeping up-to-date with research.
He is aware of those GPs using these methods in other parts
of the UK.
ECHO UK is a charity that for 10 years has provided information
on hydrogen peroxide therapy and other oxygen therapies. It
is run by Alwyne Pilsworthy and based at: Woodside, Melmerby,
Ripon, North Yorks HG4 5EZ (01765 640798).
Another is Dr Simi Khanna, in High Wycombe, Bucks, who has
been using such therapies for 10 years.
Dr Fritz Schellander, based in Tunbridge Wells, also uses
Previously based in Southampton, Dr Julian Kenyon now offers
ozone therapy in London and Winchester.
In London holistic therapist Mark Lester offers a form of
ozone treatment at his Finchley Clinic. Lester favours the
use of a steam cabinet to provide transdermal therapy which
introduces ozone via the skin while sitting in the hot steam
cabinet. Besides offering an alternative to those who don't
like injections, transdermal ozone cleanses and de-toxifies
the lymph, in which 90 percent of body fluids are stored and
which often becomes sluggish. He finds it very beneficial
for ME sufferers.
Treating HIV/AIDS successfully
The first research to show that ozone can inactivate the HIV
virus was carried out by Dr Michael Carpendale and his colleagues
at the Veterans Administration Hospital in San Francisco.
Presented to an international AIDS conference in Stockholm
in 1988, their in vitro results were published in 1991 (MT
Carpendale, JK Freeberg, Antiviral Research 1991;16:281-92).
They showed that HIV could be 99 percent inactivated by using
only 0.5 ug ozone/ml of human serum, and completely inactivated
by concentrations of 4 ug/ml of human serum, neither of which
harmed healthy cells.
Another US in vitro study, supported partly by Medizone International,
an American manufacturer of a patented ozone system, and the
US Public Health Service, found that ozone deactivated a cultured
cell medium of HIV-1 completely without causing significant
damage to non-infected cells (KH Wells et al. Blood 1991;78(7):1882).
In Russia, at Moscow's Institute of Virusology scientists
also used a concentration of 4 ug/ml of ozone on an HIV-infected
culture and within minutes the cell of the virus had decomposed
and died (GV Kornilaeva et al. in Ozone in Biology and Medicine,
Nizhni Novgorod, 1992, p.86).
A study by the Canadian Armed Forces to determine the ability
of ozone to kill HIV, hepatitis and herpes viruses in blood
for transfusion found that a three-minute ozonation of serum
spiked with 1 million HIV-1 particles per millilitre achieved
a 100 percent deactivation of the virus (AG Baggs, Can Med
Assoc J.1993; April 1:1159). As a result, the Canadian Government
sponsored a study with 24 actual AIDS patients using autohemotherapy.
Although the first phase of the study produced encouraging
increases in T-cell counts, the second phase was marred by
a faulty generator that failed to produce ozone, leading to
inconclusive results (GE Garber et al. AIDS 1991;5:981-4).
Rather than attempting a replication of this study (which
is sometimes quoted - inaccurately - as a negative result),
little interest was shown by the Canadian or any other Government
in researching the huge potential of ozonation, despite the
earlier, highly impressive, blood study results. However,
Medizone International is trying to conduct clinical trials.
In the US early studies by Dr Michael Carpendale and colleagues
in San Franciso indicated that ozone could boost T-cell counts
and eliminate infection for over five years (Ozone in Medicine:
Proc 11th Ozone World Congress, Stamford, Conn: Int Ozone
Assoc, 1993, M-1-38-43). In a further study Carpendale eliminated
intractable diarrhea in four patients after 21-28 days of
colonic insufflations of ozone (J Clin Gastroent. 1993;17:142-5).
Another study by Dr Frank Shallenberger, considered one of
the States' leading authorities on medical ozone, on five
AIDS patients produced an immediate increase in T-cells, relief
of symptoms of opportunistic infections, and higher energy
levels.(Proc: 4th Int Bio-Oxidative Medicine Conference, Oklahoma
City, IBOM, 1993). Such results have prompted other doctors,
such as Dr John Pittman, of North Carolina, to start treating
such patients with both ozone and H2O2 and to collect data
on patients receiving such therapies throughout the US.
In Germany, Dr Horst Kief, who has pioneered the development
of autohomologous immunotherapy (AHIT) using ozone, has treated
many HIV/AIDS patients since 1985. In a 1993 monograph Kief
records his success with AIDS patients, reporting in one study
of 27 patients that 80 percent survived longer than 18 months
and 70 percent longer than 45 months, representing a much
higher percentage than those treated conventionally (Ozone
and the AHIT Therapy in AIDS Patients, Ludwigshafen, Kief
This follows a report on four patients treated by Dr Alexander
Preuss in 1986 in which he reported their immediate improvement
and elimination of skin diseases, fungal infections, gastrointestinal
problems and low energy (OzoNachrichten 1986;5:3-5). One year
later all patients were considered clinically healthy. At
present Dr Juliane Sacher of Frankfurt has one of the largest
medical practices treating AIDS patients with ozone.
How bio-oxidative therapies work
Leading US authority, Nevada-based Dr Frank Shallenberger
has outlined their effects in Nathaniel Altman's Oxygen Healing
Therapies (essential reading for those seeking the scientific
evidence, p.19, see main text) as follows:
- They stimulate production of white blood cells, necessary
to fight infection;
- Ozone and hydrogen peroxide are virucidal;
- Both increase oxygen and hemoglobin disassociation, thus
increasing delivery of oxygen from blood to cells;
- Both are anti-neoplastic, inhibiting the growth of new
tissues like tumours;
- Bio-oxidative therapies oxidize and degrade petrochemicals;
- They increase red blood cell membrane distensibility,
thus enhancing their flexibility and effectiveness;
- They increase the production of interferon and tumour
necrosis factor, used to fight infection and cancer;
- They increase the efficiency of the antioxidant enzyme
system, which scavenges excess free radicals;
- They accelerate the citric acid cycle, the main cycle
for liberating energy from sugars, which then stimulates
- These therapies increase tissue oxygenation, which brings
about patient improvement.
Another important fact is that cancer cells are weakened
through fermentation, which produces only 1/19 the amount
of ATP compared to oxidation, and therefore are chronically
short of energy, which renders them unable to manufacture
the anti-oxidant enzymes glutathione peroxidase, superoxide
dismutase, catalase and reductase that protect every normal
cell from oxidative destruction. Thus they are completely
vulnerable to cell lysis by ozone and H2O2.
By flooding the body with oxygen, these therapies aim to maximise
biological 'combustion' of both energy supplies and toxins
through proper oxidation, enabling elimination of toxic substances
and boosting of the immune system. Factors leading to oxygen
deficiency include devitalised food, poor breathing, lack
of exercise and air pollution: 100 years ago the percentage
of oxygen in the air was around 22%; today it is 19%, and
even less in very polluted cities.
A word of caution: both ozone and hydrogen peroxide are toxic
in their purified states (ozone is potentially damaging to
the lungs if inhaled), but are safe and effective when diluted
to therapeutic levels and administered by an experienced practitioner,
who should be consulted before starting any course of treatment.
The suppression of oxygen-ozone therapies
The American Federal Drug Administration (FDA) has a history
of harassing doctors using ozone generators, which are presently
outlawed in many states. The leading US campaigning journalist
Ed McCabe, author of Oxygen Therapies (see main text), recounts
the saga around their refusal, until very recently, to allow
human trials of ozone therapy, accused of defending drug companies'
vested interests. Clinics have been closed down and doctors
threatened with having their licenses revoked with they administer
ozone or hydrogen peroxide. According to McCabe, in 1975 the
US Government General Accounting Office studied the FDA and
revealed that 150 FDA officials owned stock in the companies
they were supposed to be regulating.
Perhaps the best known case, according to Nathaniel Altman
(Oxygen Healing Therapies), is that of Dr Robert Atkins, director
of the Atkins Center for Complementary Medicine in New York,
who had his licence revoked by the FDA for treating patients
with ozone. In 1993 his successful court case against New
York State to regain his license resulted in the passing of
a law permitting physicians to use ozone and other non-FDA-approved
Many of the battles to get such therapies recognised are recorded
in the award-winning 1993 documentary Ozone and The Politics
of Medicine produced by Geoffrey Rogers of Threshold Film,
Vancouver, B.C, which is available on video.